Archive for November, 2006
Teva Announces Tentative Approval Of Sumatriptan Succinate Tablets
Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA) announced today that the U.S. Food and Drug Administration has granted tentative approval for the Company’s Abbreviated New Drug Application (ANDA) for Sumatriptan Succinate Tablets, 25 mg, 50 mg and 100 mg. Final approval is expected upon expiry of patent protection for the brand product in February 2009. [click link for full article]
Original post by It’s My Life, People
No commentsIndividual differences in anatomy predict reading and oral language impairments in children
Developmental dyslexia (DD) and specific language impairment (SLI) are disorders of language that differ in diagnostic criteria and outcome. DD is defined by isolated reading deficits. SLI is defined by poor receptive and expressive oral language skills. Reading deficits, although prevalent, are not necessary for the diagnosis of SLI. An enduring question is whether these two disorders are qualitatively different or simply differ quantitatively along a dimension of severity. Here we address this problem by examining neuroanatomical correlates of reading and language in children with learning disabilities. We asked whether a quantitative anatomical risk index derived from previous work could predict behavioural profiles in a heterogeneous sample of 14 boys and 8 girls (11–16 years of age) with reading and language impairments. The results confirmed our predictions that (i) children with relatively smaller and symmetrical brain structures (negative risk indices) would have the severe comprehension impairments typical of SLI; (ii) children with larger, asymmetrical brain structures (positive risk indices) would have poor word reading in the presence of relatively preserved comprehension, a profile typical of DD; and (iii) the best performance would be seen in children with anatomical risk indices near zero (normal anatomy). Also, in confirmation of previous work, rapid automatic naming was not predicted by the anatomical risk index, but by anatomical measures derived from the frontal lobes. These results highlight the key significance of comprehension deficits in distinguishing DD from SLI. Reading impaired children with and without comprehension deficits appear to occupy neuroanatomical domains on the opposite sides of normal. (Source: Brain)
Original post by Brain
No commentsGrant To Establish Center For Lupus Research: Baylor Research Institute Receives $6.2 Million
Baylor Research Institute has received a $6.2 million grant that will allow its immunology division, Baylor Institute for Immunology Research (BIIR), to establish a Center for Lupus Research. The grant comes from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, one of the National Institutes of Health.Lupus is an autoimmune disease, which means that a person’s immune system attacks their own body. [click link for full article]
Original post by It’s My Life, People
No commentsHerbal Medication Relieves Painful Migraine Headaches
Raghu Bajwa MD, Chairwoman of Guruji Herbal, Inc. announced the availability of Migrowin(C)(R)(TM) at the Complementary and Natural Healthcare CAM EXPO. Twenty five Million Americans, about 17 percent of women and 7 percent of men suffer from migraine headaches. This debilitating affliction occurs on a recurring basis, is extremely painful and affects the quality of life of people suffering from it. [click link for full article]
Original post by It’s My Life, People
No commentsReplication of reported linkages for dyslexia and spelling and suggestive evidence for novel regions on chromosomes 4 and 17
(Source: European Journal of Human Genetics)
Original post by European Journal of Human Genetics
No commentsVascular Endothelial Growth Factor (VEGF) Gene Therapy Using A Non-Viral Gene Delivery System Improves Erectile Dysfunction In A Diabetic Rat Model
UroToday.com – In light of the fact that VEGF has shown to improve overall endothelial and smooth muscle cell dysfunction in models of ED and (ED) decreases the quality of life in more than 70% of diabetic men, the authors investigate the ability to achieve in in-vivo gene transfection of VEGF in the rat model. Diabetes was induced and confirmed with a single injection of streptozotocin. [click link for full article]
Original post by It’s My Life, People
No commentsPhonological but not auditory discrimination is impaired in dyslexia
European Journal of Neuroscience Volume 0, Issue 0, Page ???-???. (Source: European Journal of Neuroscience)
Original post by European Journal of Neuroscience
No commentsThe attentional blink reveals sluggish attentional shifting in adolescents with specific language impairment.
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The attentional blink reveals sluggish attentional shifting in adolescents with specific language impairment.
Brain Cogn. 2006 Nov 20;
Authors: Lum JA, Conti-Ramsden G, Lindell AK
Rapid processing deficits have been the subject of much debate in the literature on specific language impairment (SLI). Hari and Renvall (2001) [Hari, R. & Renvall, H. (2001). Impaired processing of rapid stimulus sequences in dyslexia. Trends in cognitive sciences, 5, 525-532.] proposed that the source of this deficit can be attributed to sluggish attentional shifting abilities. That is, more time is required to shift attention between stimuli. To test this claim, 26 adolescents with SLI (divided into two subgroups to control for differences in non-verbal intelligence) and 14 controls were presented with a rapid serial visual presentation task. In this task participants were asked to detect two visual targets presented serially with distracter items with varying inter-target intervals (i.e., time difference between targets). This task was designed to elicit an attentional blink (AB). The AB describes the phenomenon whereby non-impaired individuals are less likely to report the second of two targets presented within 200-500ms of each other. After controlling for group differences in non-verbal intelligence, the SLI group was found to be significantly less accurate than the control group at successfully reporting the second target at inter-target intervals of 100, 200, 300, 400 and 800ms. The results were interpreted to suggest that adolescents with language impairments have an AB which differs from non-impaired individuals in both magnitude and duration.
PMID: 17118504 [PubMed - as supplied by publisher]
(Source: Brain and Cognition)
Original post by Brain and Cognition
No comments‘please look after the poor wee boy at the back’
Sir Jackie Stewart tells David Leafe why his own miserable schooldays made him determined to help children with dyslexia (Source: Telegraph Health)
Original post by Telegraph Health
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