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Archive for December, 2006

Involvement Of The Amygdala In Systemic Lupus Erythematosus

In a mouse model of systemic lupus erythematosus (SLE), anti-NMDA receptor antibodies have been shown to gain access to the brain during stress, specifically damaging the amygdala (a part of the brain that is involved in emotion) and causing altered emotional responses. [click link for full article]

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Methylphenidate improves reading performance in children with attention deficit hyperactivity disorder and comorbid dyslexia: an unblinded clinical trial.

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Methylphenidate improves reading performance in children with attention deficit hyperactivity disorder and comorbid dyslexia: an unblinded clinical trial.

Eur J Paediatr Neurol. 2007 Jan;11(1):21-8

Authors: Keulers EH, Hendriksen JG, Feron FJ, Wassenberg R, Wuisman-Frerker MG, Jolles J, Vles JS

Attention Deficit Hyperactivity Disorder (ADHD) and dyslexia are frequently co-occurring disorders. Although methylphenidate (MPH) is the primary treatment for ADHD, the effect on reading in children with these comorbid problems is not yet known. This study was an unblinded clinical trial to evaluate the reading performance before and after treatment with MPH. Reading performance was compared with General Linear Model repeated measures between three groups: (1) an experimental group of children with both ADHD and dyslexia (N = 24), (2) a control group of children with ADHD (N = 9) and (3) a control group of children with dyslexia (N = 10). MPH improved reading performance significantly stronger in the experimental group than in the control groups; the number of correctly read words increased to a larger extent. In conclusion, MPH proved to be an aid in the reading process of children with ADHD and comorbid dyslexia by improving the learning conditions, but MPH cannot cure the reading disorder. Future research should study the effect of MPH on reading in a double-blind clinical trial.

PMID: 17169593 [PubMed - indexed for MEDLINE]

(Source: European Journal of Paediatric Neurology)

Original post by European Journal of Paediatric Neurology

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New Dyslexia Theory Blames ‘Noise’

The dyslexic brain struggles to read because even small distractions can throw it off, according to a new model of dyslexia emerging from a group of recent studies.The studies contradict an influential, 30-year-old theory that blamed dyslexia on a neural deficit in processing the fast sounds of language.Instead, the studies suggest that children with dyslexia have bad filters for irrelevant data. [click link for full article]

Original post by Allergy News From Medical News Today

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Fear Of Migraine Destroys Quality Of Life For Men

The unpredictability of symptoms and apprehension associated with living with migraine is limiting mens’ lives, according to research from Griffith University’s Genomics Research Centre.Although migraine is more common in women than men, about 6% of Australian men live with the debilitating neurological condition characterised by chronic headaches, sensitivity to light, visual symptoms and nausea. [click link for full article]

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Low Impact Aerobic Exercise Reduces Fatigue In Auto-immune Conditions Says Multi-study Review

Low impact aerobic exercise, such as walking and cycling, can effectively reduce fatigue in adults with chronic auto-immune conditions, according to a research review in the latest issue of the UK-based Journal of Advanced Nursing.A team led by nurse researcher Dr Jane Neill from Flinders University in Adelaide, examined 162 research studies published between 1987 and 2006, analysing 36 in detail. [click link for full article]

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Evidence for frequent divergence impairment in french dyslexic children: deficit of convergence relaxation or of divergence per se?

AbstractAim??There is a controversy as to whether dyslexic children present visuo-motor disabilities such as vergence and accommodative problems assessed with orthoptic tests. The purpose of this study is to re-examine this issue in a large population of children.Methods??Extensive orthoptic evaluation was made in 57 dyslexic and 46 non-dyslexic (?normal?) age-matched children. Convergence and divergence capacities were evaluated at two distances (30?cm and 400?cm).Results??Binocular vision measured with stereo-acuity tests was normal in dyslexics. In contrast, the near point of convergence was significantly more remote in dyslexics; most importantly, divergence at both far and near distance was significantly more reduced in dyslexics (median value 4?pD and 10?pD, respectively, at far and near) than in ?normals? (median value 6?pD and 12?pD, at far and near).Conclusion??The existence of the divergence deficit at far distance indicates the presence of deficit of divergence per se, independently from convergence and accommodation relaxation. This result is novel and corroborated by physiological studies indicating distinct control of convergence and divergence, both at the cortical and subcortical premotor level. We conclude that vergence deficits are frequently present in dyslexics, and that dyslexics should be re-educated; training should address distinctively convergence and divergence subsystems.
Content TypeJournal Article

JournalGraefe’s Archive for Clinical and Experimental OphthalmologyOnline ISSN 1435-702XPrint ISSN 0721-832X (Source: Graefe’s Archive for Clinical and Experimental Ophthalmology)

Original post by Graefe’s Archive for Clinical and Experimental Ophthalmology

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IDIBAPS Validates The First Prognostic DNA Chip

The European Union, in the Sixth Framework Programme (FP6), has approved a project led by IDIBAPS-Hospital Clínic with the aim to validate the IBDchip within the European Community. Being the world’s first diagnostic DNA chip, it has the main object to predict prognosis and response to therapy of patients suffering from inflammatory bowel disease. The programme has a 2. [click link for full article]

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A survey-based exploration of the impact of dyslexia on career progression of uk registered nurses

Volume 15, Issue 1, Page 97-106, Jan 2007. (Source: Journal of Nursing Management)

Original post by Journal of Nursing Management

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Alexza Completes Enrollment In AZ-001 Phase IIb Clinical Trial In Patients With Migraine Headaches

Alexza Pharmaceuticals, Inc. (Nasdaq: ALXA) announced today that it has completed patient enrollment in its Phase IIb clinical trial of AZ-001 (Staccato(R) prochlorperazine) in patients with migraine headaches. AZ-001 is an inhalation product candidate being developed for the acute treatment of migraine headaches. [click link for full article]

Original post by It’s My Life, People

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New dyslexia theory blames ‘noise’ — poor filtering of unwanted data may be root cause

Kids with dyslexia can’t block out distractions, say a group of new studies. The results cast doubt on an influential neurological model of dyslexia developed in the 1970s. (Source: ScienceDaily Headlines)

Original post by ScienceDaily Headlines

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