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Archive for the 'Liver Disease' Category

Post-Liver Transplantation Survival May Be Predicted By Cardiopulmonary Exercise Testing

Researchers from the U.K. determined that preoperative cardiopulmonary exercise testing (CPET) is a specific predictor of 90-day survival following liver transplantation…

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New Information In The Fight Against Flu

Influenza virus can rapidly evolve from one form to another, complicating the effectiveness of vaccines and anti-viral drugs used to treat it…

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Live Liver Donations Confirmed As Safe

According to Johns Hopkins researchers, individuals who donate a portion of their liver for live transplantation usually recover safely from the procedure and can expect to live long, healthy lives. The study is published in the February issue of the journal Gastroenterology. Dorry L. Segev, M.D., Ph.D…

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Many High-Risk Americans Don’t Get Hepatitis B Vaccine

A recently published study investigating hepatitis B vaccination rates in the United States found that more than half of adults at risk for hepatitis B virus remain unvaccinated. With many of these individuals making contact with the healthcare system, including HIV testing, this statistic reflects many missed opportunities to vaccinate this population…

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Small Changes In The Genome Account For Gender Differences In Liver Cancer Risk

Men are four times more likely to develop liver cancer compared to women, a difference attributed to the sex hormones androgen and estrogen. Although this gender difference has been known for a long time, the molecular mechanisms by which estrogens prevent – and androgens promote – liver cancer remain unclear…

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Common Type Of Hepatitis C Suppressed By Combination Of Oral Drugs

A new combination of investigational drugs successfully suppressed hepatitis C genotype 1 infection in a high percent of patients who had not responded to previous treatment in a study led by a University of Michigan hepatologist. The study, which was published Jan…

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Researchers Identify Modifiable Risk Factors That Could Limit The Incidence Of Post-Transplant End-Stage Renal Disease

Research from the University of Michigan Health System shows the risk for kidney failure among liver transplant recipients is higher following the implementation of Model of End Stage Liver Disease (MELD), a policy change in 2002 that altered how liver transplant allocation is decided. The study, led by Pratima Sharma, M.D., M.S…

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Pediatric Liver Transplant Graft Recipients Can Stay Off Immunosuppressant Medications

A study in the January 18 issue of JAMA reveals that the majority of children who received liver transplant grafts from a parent were able to stay off immunosuppression therapy for at least 1 year with normal graft function after gradual withdrawal from the therapy…

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Potential New Therapy Approach For Hepatitis C Could Benefit 170 Million People Affected Worldwide

Researchers at the University of British Columbia have found a new way to block infection from the hepatitis C virus (HCV) in the liver that could lead to new therapies for those affected by this and other infectious diseases. More than 170 million people worldwide suffer from hepatitis C, the disease caused by chronic HCV infection…

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Blocking Cell-To-Cell Communication May Prevent Liver Damage And Improve Drug Safety

Massachusetts General Hospital (MGH) investigators have developed a novel strategy to protect the liver from drug-induced injury and improve associated drug safety…

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