Archive for the 'Lupus' Category
Mutation Drives Viral Sensors To Initiate Autoimmune Disease
A new study uses a mouse model of a human autoimmune disease to reveal how abnormal regulation of the intracellular sensors that detect invading viruses can lead to autoimmune pathology…
Original post by Wife of a Diabetic
No commentsDNA Sequence Discovered That Causes The Most Severe Cases Of Lupus
A “genetic accelerator” is responsible for the most severe cases of Lupus (systemic lupus erythemathosus), an autoimmune disease: the accelerator, called enhancer HS1.2, speeds up the activity of some critical genes of the immune system involved in the disease. A team of Italian researchers at the Catholic University of Sacred Heart in Rome found that the enhancer HS1…
Original post by Wife of a Diabetic
No commentsStudy: Mycophenolate Is Superior To Azathioprine As Treatment For Lupus Nephritis
A new large, international study finds that the immunosuppressant drug mycophenolate mofetil is superior to azathioprine, an older immunosuppressant, as a maintenance therapy for lupus nephritis…
Original post by Wife of a Diabetic
No commentsHemodialysis Therapy Preferred By Most Lupus Nephritis Patients With End-Stage Renal Disease
Newly published research shows that more patients with end-stage renal disease (ESRD) caused by lupus nephritis choose hemodialysis as their initial kidney replacement therapy over peritoneal dialysis and preemptive kidney transplantation…
Original post by Wife of a Diabetic
No commentsTransportation And Childcare Difficulties Top Reasons For Missed Lupus Appointments
The first step towards successful medical care is to see a physician, but for some patients this isn’t as simple or easy as it may sound. A study presented at the 2011 Annual Scientific Meeting of the American College of Rheumatology in Chicago, finds that many lupus patients with low socioeconomic status are unable to attend scheduled appointments with physicians due to daily obstacles…
Original post by Wife of a Diabetic
No commentsSuccessful Pregnancy Outcomes For Most Women With Lupus
Promising research led by investigators at Hospital for Special Surgery may offer hope for women with lupus who once thought that pregnancy was too risky. Results from the multicenter National Institutes of Health (NIH) funded PROMISSE initiative, being presented Monday, Nov. 7 and then during a press conference on Tuesday, Nov…
Original post by Wife of a Diabetic
No commentsXToll Completely Prevented Cutaneous Lupus In Animal Study
CBio Limited have announced the publication of their animal trial on the advanced access site of the Oxford Journals publication, Nephrology Dialysis Transplantation. The research is titled – “Recombinant chaperonin10 (Xtoll) suppresses cutaneous lupus and lupus nephritis in MRL-(Fas)lpr mice.” According to results of the study, using XToll to treat mice completely prevented cutaneous lupus…
Original post by Wife of a Diabetic
No commentsAlthough Atorvastatin Fails To Slow Progression Of Atherosclerosis In Pediatric Lupus Patients, It Is Safe And May Help With More Severe Lupus
Atorvastatin therapy was found to be ineffective in reducing atherosclerosis progression in children and adolescents with systemic lupus erythematosus (SLE)…
Original post by Wife of a Diabetic
No commentsA Simpler System Would Make It Easier For Clinicians To Treat Kidney Problems In Lupus Patients
The current classification system for kidney complications in patients with lupus is too detailed, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results should make it easier for physicians to classify and treat kidney problems in patients with the disease…
Original post by Wife of a Diabetic
No commentsStatins Disappoint In Atherosclerosis Progression In Children With Lupus
According to the American College of Rheumatology (ACR) 322,000 adult Americans are affected by systemic lupus erythematosus (SLE) with approximately 5,000 to 10,000 children in the U.S. affected by lupus (Lehman 1996), although exact figures for pediatric SLE cases remain difficult to establish…
Original post by Wife of a Diabetic
No comments