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Archive for the 'Lymphoma / Leukemia' Category

AL Amyloidosis – Bortezomib, Cyclophosphamide, And Dexamethasone Combo Shows Promise

Two studies have registered a preliminary success of an effective multiple myeloma (MM) regimen in patients with AL amyloidosis. The studies have been published in Blood, the Journal of the American Society of Hematology (ASH)…

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Targeting Leukemia Stem Cells

New research takes aim at stubborn cancer stem cells that are thought to be responsible for treatment resistance and relapse…

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News From The Journal Of Clinical Investigation: Feb. 13, 2012

METABOLIC DISEASE: A direct hit from the hormone leptin has potential therapeutic consequences The number of people who suffer from one or more of the adverse complications of obesity, including type 2 diabetes, is rapidly increasing. The hormone leptin decreases food intake and increases energy expenditure. As such, it was hoped that it could be developed as an anti-obesity agent…

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Childhood Leukemia Drug, Methotrexate, In Short Supply

Methotrexate, a drug used to treat acute lymphoblastic leukemia, the most common childhood leukemia, is now also in short supply in the USA, along with several other lifesaving drugs. According to the FDA, vital lifesaving hospital drugs have not been so scarce in ten years. Methotrexate works by slowing down the rate at which cancer cells grow…

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Highlighting A Rare Subset Of Diseases Involving The Lymphatic System

A clinically challenging and under-studied subset of diseases affecting the lymphatic system and grouped under the disease spectrum lymphangiomatosis and Gorham’s disease is the focus of a special issue of Lymphatic Research and Biology, a peer-reviewed journal published by Mary Ann Liebert, Inc.. The issue is available free online…

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Treating Canine Lymphoma

A new immunotherapy for companion dogs with advanced-stage non-Hodgkin lymphoma (NHL) has been shown to improve survival while maintaining quality of life, according to a study published in the journal Scientific Reports…

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Inherited Risk Factors For Childhood Leukemia Are More Common In Hispanic Patients

Hispanic children are more likely than those from other racial and ethnic backgrounds to be diagnosed with acute lymphoblastic leukemia (ALL) and are more likely to die of their disease. Work led by St. Jude Children’s Research Hospital scientists has pinpointed genetic factors behind the grim statistics…

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Leukemia Cells Are “Bad To The Bone”

University of Rochester Medical Center researchers have discovered new links between leukemia cells and cells involved in bone formation, offering a fresh perspective on how the blood cancer progresses and raising the possibility that therapies for bone disorders could help in the treatment of leukemia. The research, led by graduate student Benjamin J. Frisch in the James P…

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A Leukemia Drug Kills Cancerous T-Cells While Sparing Normal Immunity

Leukemic cutaneous T-cell lymphoma (L-CTCL) is a leukemia arising from T-cells, a type of white blood cell. This cancer can involve the skin and other organs, and patients often die within three years. Rachael A…

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Breast Cancers And Leukemias Slowed By A Single Therapy

Targeting a single protein can help fight both breast cancers and leukemias, according to two reports published online in the Journal of Experimental Medicine. The single protein is HSP90, which acts as a chaperone to protect other proteins in the cell…

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